EGTA(ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid) 

≥97% Molecular biology grade

货号：ME0732-5g   200.00

别名: Ethylenebis(oxyethylenenitrilo)tetra(acetic acid) Titriplex® VI Kestranal® FE PA Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid Idranal® VI

Physical Appearance: White Powder
pKa: 2, 2.7, 8.8, and 9.5 (Lit.)
溶解度: Soluble in alkaline solutions (1 g in 10 mL 1 N NaOH + 50 mL water-clear, colorless solution).
典型工作浓度: as a metalloprotease inhibitor (effective concentration is typically 1 to 10 µM)
Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent. It is an inhibitor of alkaline phosphatase activity which is useful in ELISA reactions.
Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.